Description
💊 Auvelity 45-105 mg – Fast-Acting Oral Antidepressant for Major Depressive Disorder (MDD)
Auvelity 45-105 mg is a prescription medication developed for the treatment of major depressive disorder (MDD) in adults. It’s the first and only oral NMDA receptor antagonist approved by the FDA for depression, offering a unique dual-action formula that can deliver significant symptom relief within one week—far quicker than many traditional antidepressants.
This innovative medication combines two active ingredients:
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Dextromethorphan HBr (45 mg) – works on NMDA receptors in the brain, helping rebalance key neurotransmitters involved in mood regulation.
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Bupropion HCl (105 mg) – a dopamine and norepinephrine reuptake inhibitor (DNRI) that further supports emotional stability and energy levels.
How Does Auvelity Work?
Unlike SSRIs and SNRIs, which often take 4–6 weeks to show full results, Auvelity acts rapidly, thanks to the combined mechanism of NMDA modulation and dopaminergic support. This dual pathway approach enhances synaptic plasticity and neurochemical balance, which may contribute to the faster relief of depressive symptoms.
Benefits of Auvelity 45-105 mg
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✅ Rapid onset—relief often felt in 7 days
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✅ Treats symptoms of MDD effectively
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✅ First-of-its-kind oral NMDA receptor antagonist
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✅ Once-daily capsule for convenience
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✅ Ideal for patients with inadequate SSRI/SNRI response
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✅ Improves mood, motivation, and mental clarity
How to Take Auvelity
Take one capsule daily by mouth, with or without food. Swallow the capsule whole; do not crush, chew, or split it. Always follow your healthcare provider’s instructions. Do not use in combination with MAOIs or other forms of bupropion unless specifically prescribed.
⚠️ Important: Auvelity is a prescription-only medication. Always consult your doctor before starting or discontinuing treatment. Be aware of potential side effects, including dizziness, dry mouth, or increased blood pressure.
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